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Discovery, Design, and Synthesis of Indole-Based Ezh2 Inhibitors

Victor S. Gehling,Rishi G. Vaswani,Christopher G. Nasveschuk,Martin Duplessis,Priyadarshini Iyer,Srividya Balasubramanian,Feng Zhao,Andrew C. Good,Robert Campbell,Christina Lee,Les A. Dakin,Andrew S. Cook,Alexandre Gagnon,Jean-Christophe Harmange,James E. Audia,Richard T. Cummings,Emmanuel Normant,Patrick Trojer,Brian K. Albrecht

Bioorganic & medicinal chemistry letters（2015）

Cited 58|Views84

Key words

EZH2,PRC2,Histone methyltransferase,Epigenetics,Pyridone

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