Adrenohepatic fusion: Adhesion or invasion in primary virilizant giant adrenal carcinoma? Implications for surgical resection. Two case report and review of the literature

•Since its first description, by Dolan, in 1968, called adrenal dystopia, described as the union between the adrenal gland and the liver parenchyma, the adreno-hepatic fusion (AHF) counts on less than 90 articles in PubMed.•In our experience, in spite of a little known entity, AHF may be a primary pathological entity that largely determines the surgical behavior, which in our experience results in terms of long-term and disease-free survival for the patient.•The absence of capsulla between the liver and the adrenal gland means that the lesion must be resected as a whole, even with right hepatectomy, in order to extirpate all the microscopic intermingling between the two parenchymas.•This case report underlines the importance of the detection of adrenohepatic fusion before the intervention, whose presence may compromise both resectability and survival.•We present two consecutive cases of adrenal carcinoma with AHF treated in a reference unit of liver surgery, emphasizing the key points that helped improve the disease-free survival.