In Vitro Evaluation of the Effect of 7-Methyl Substitution on Glucuronidation of Daphnetin: Metabolic Stability, Isoform Selectivity, and Bioactivity Analysis.
Journal of pharmaceutical sciences（2015）
Key words
daphnetin,glucuronidation,methyl substitution,structural modification,metabolic stability,phase II enzymes,glucuronosyl-transferases,human liver microsomes,enzyme kinetics,metabolic clearance
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