Nonspecific Interstitial Pneumonia Associated With Dermatomyositis With And Without Anti-Jo-1 Autoantibodies
AJSP-REVIEWS AND REPORTS(2013)
Abstract
Nonspecific interstitial pneumonia is a type of diffuse parenchymal lung disease characterized by interstitial inflammation and fibrosis, without the heterogeneous distribution and peripheral honeycombing, typical of usual interstitial pneumonia (UIP). It is seen in 2 settings as follows: as an idiopathic disease and associated with a variety of other, including rheumatologic, disorders. There is evidence that patients with idiopathic nonspecific interstitial pneumonia often have some autoimmune manifestations that do not fulfill criteria for a specific rheumatologic disease and therefore manifest as a primary autoimmune lung disease. Diffuse lung injury may occur in established cases as a superimposed process (acute exacerbation), similar to UIP, or be present at initial presentation. The distinction from UIP is important because the prognosis is generally far better.
MoreTranslated text
Key words
interstitial pneumonia, pulmonary fibrosis, dermatomyositis, polymyositis, anti-Jo-1
AI Read Science
Must-Reading Tree
Example
![](https://originalfileserver.aminer.cn/sys/aminer/pubs/mrt_preview.jpeg)
Generate MRT to find the research sequence of this paper
Chat Paper
Summary is being generated by the instructions you defined