Reading, listening and memory-related brain activity in children with early-stage temporal lobe epilepsy of unknown cause-an fMRI study

Katariina Mankinen, Pieta Ipatti,Marika Harila,Juha Nikkinen,Jyri-Johan Paakki,Seppo Rytky,Tuomo Starck,Jukka Remes,Maksym Tokariev,Synnöve Carlson,Osmo Tervonen,Heikki Rantala,Vesa Kiviniemi

European Journal of Paediatric Neurology（2015）

Cited 6|Views25

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Abstract

•TLE patients showed significantly different BOLD response in a story listening task.•Differences were found in the temporal structures, thalamus and basal ganglia.•Patients with abnormal EEG showed increased activation.•Patients with normal EEG showed increased deactivation outside the temporal structures.•TLE entails a widespread disruption of brain networks.

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Key words

Functional magnetic resonance imaging,Blood oxygenation level-dependent response,Paediatric temporal lobe epilepsy,Learning

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