Chemical constituents from a Chinese fern Polypodium hastatum Thunb.

Phytochemical investigation on a Chinese fern Polypodium hastatum resulted in the isolation of three flavonoid glycosides, one steroid and one coumarin. Their structures were identified as β-sitosterol (1), coumarin (2), juglanin (3), kaempferol-7-O-α-l-rhamnopyranoside (4) and (+)-afzelechin-5-O-β-d-apiofuranoside (5) on the basis of spectroscopic analysis including UV, MS, 1D and 2D NMR, and chemical and physical properties. (+)-Afzelechin-5-O-β-d-apiofuranoside was a new flavonoid glycoside. Chemotaxonomic significance of this investigation was summarized.