Effectiveness of Pilates exercise: a quality evaluation and summary of systematic reviews based on randomized controlled trials

•This is the first systematic review (SR) of systematic reviews of the effectiveness of treatment and health enhancement based on Pilates exercise (PE) in studies with randomized controlled trial (RCT) designs.•Our study is unique because it summarized the evidence for each target disease according to the International Classification of Diseases-10.•We propose the future research agenda for studies on the effect of PE.