The Effects of Brovincamine on the Common Carotid Hemodynamics in Patients with Cerebral Circulatory Insufficiency

This study was performed to clarify the effects of brovincamine on the common carotid hemodynamics in patients with cerebral circulatory insufficiency.A total of 38 patients including 14 males and 24 females were enrolled in this study. Their ages ranged from 55 to 84 years old and the mean age was 72 years old. They were given orally 60mg of brovincamine daily for 6 months. The common carotid hemodynamics by ultrasonic quantitative flow measurement system were evaluated during brovincamine administration.Mean blood flow and mean blood velocity of the common carotid artery significantly increased in 1, 3, and 6 months after therapy. On the other hand, circulatory resistance of the brain significantly decreased in 1, 3, and 6 months after therapy.These results indicate that brovincamine therapy may have beneficial effects on the common carotid hemodynamics in patients with cerebral circulatory insufficiency.