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Targeting Metabolomics in Breast Cancer

Current Breast Cancer Reports(2012)

Cited 4|Views35
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Abstract
Metabolomics is a science that provides a dynamic portrait of the metabolic status of a biological system. Down from genomics, transcriptomics, and proteomics, metabolomics assesses end product metabolites and small intermediate molecules. In oncology, identification and quantification of metabolites and correlation with critical metabolic pathways in carcinogenesis may provide insight into tumoral biology. In breast cancer, promising early work suggests that metabolomics might enhance current clinical practice by refining biological subclassification, improving prediction of recurrence, and aiding in treatment decisions.
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Key words
Metabolomics,Metabolite,Breast cancer,Early breast cancer,Oncology,Nuclear magnetic resonance,Mass spectroscopy,Screening,Detection,Tissue diagnosis,Recurrence,Treatment,Outcomes,Metastatic disease,Micrometastatic disease,Subclassification of breast cancers
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