Effects of d-amphetamine and pilocarpine on the mouse-killing response of hungry and satiated rats

Abstract Two experiments examined some relationships between feeding schedule and two psychoactive drugs on the mouse-killing response in rats. Experiment 1 showed that the combination of a high dose of d-amphetamine (2.00 mg/kg) and food satiation effectively suppresses killing while either factor alone does not. Experiment 2 showed that the combination of a high dose of pilocarpine (30 mg/kg) and food deprivation induces a considerable percentage of Sprague-Dawley rats to kill mice while either variable alone does not.