[Study on Effective Parts of Ficus microcarpa Leaves by Serum HPLC Fingerprint].

OBJECTIVE:To study the relevance between the drug effects and serum HPLC fingerprint of chemical constituents in blood from Ficus microcarpa leaves. METHODS:Fingerprints of the preparation and drug-containing serum of rats were established by HPLC. Based on the fingerprints, chemical constituents in blood were investigated. RESULTS:There were seven common peaks in the HPLC fingerprints of drug-containing serum of rats. Polarity fraction of the chemical constituents in blood existed in the ethyl acetate extract, and five fingerprint peaks of serum HPLC fingerprint existed in n-butanol extract. CONCLUSION:Determination of the component groups in blood provides some data on material basis study in vivo for Ficus microcarpa leaves.