Produced an infectious ferret hepatitis E virus in human hepatocarcinoma cell line PLC/PRF/5.

Tian-Cheng Li,Sayaka Yoshizaki,Tingting Yang,Michiyo Kataoka,Tomofumi Nakamura,Yasushi Ami,Suzaki Yuriko,Naokazu Takeda,Takaji Wakita

Virus Research（2016）

引用 13|浏览9

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摘要

•A cell culture system for ferret HEV was established.•The ferret HEV particles were associated with cell membrane.•The ferret HEV grown in PLC/PRF/5 was infectious.•The ferret HEV cell culture system might be useful to understand the life cycle, mechanism of infection and replication of ferret HEV.

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关键词

Ferret HEV,Cell culture,PLC/PRF/5,Infectivity

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