Parallel single-cell sequencing links transcriptional and epigenetic heterogeneity

Christof Angermueller,Stephen J Clark,Heather J Lee,Iain C Macaulay,Mabel J Teng,Tim Xiaoming Hu,Felix Krueger,Sébastien A Smallwood,Chris P Ponting,Thierry Voet,Gavin Kelsey,Oliver Stegle,Wolf Reik

NATURE METHODS（2016）

引用 540|浏览75

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摘要

Parallel, genome-wide methylation and transcriptional profiling from a single cell (scM&T-seq) enables the discovery of associations between transcriptional and epigenetic variation.

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关键词

RNA sequencing,Gene expression,Epigenetics,Methylation analysis

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