Comparative genomic analysis of the swine pathogen Bordetella bronchisepticastrain KM22.

Veterinary Microbiology(2016)

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摘要
•The KM22 genome sequence is similar to other B. bronchiseptica strains isolated from animals.•bopN, bvgA, fimB, and fimC were the most highly conserved BvgAS-regulated genes present in all strains analyzed.•BvgAS-regulated genes with the highest sequence divergence werefimN, fim2, fhaL, and fhaS.•A total of eight major fimbrial subunit genes were identified in KM22.•qPCR data demonstrated that seven of the eight fimbrial subunit genes are expressed and regulated by BvgAS.
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关键词
Bordetella,Genome sequence,Swine
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