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Bicyclic heterocyclic anthranilic diamides as ryanodine receptor modulators with insecticidal activity.

André Jeanguenat, Patricia Durieux,Andrew J F Edmunds,Roger G Hall,Dave Hughes,Olivier Loiseleur,Jagadish Pabba,André Stoller,Stephan Trah,Jean Wenger, Anna Dutton,Andrew Crossthwaite

Bioorganic & medicinal chemistry（2015）

Cited 17|Views15
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Abstract
The diamide insecticides act on the ryanodine receptor (RyR). The synthesis of various bicyclic anthranilic derivatives is reported. Their activity against the insect ryanodine receptor (RyR) and their insecticidal activity in the greenhouse is presented, as well as structure activity relationship considerations.
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