The etiologic subtype of intracerebral hemorrhage may influence the risk of significant hematoma expansion.

•ICH etiologic subtype may influence the risk of massive hematoma expansion.•Amyloid angiopathy-related ICH was the etiologic subtype with lower risk of growth.•Anticoagulant-related ICH was the etiologic subtype with higher risk of growth.•Baseline ICH volume and onset to baseline CT time were predictors of growth.