Emerging roles of A-kinase anchoring proteins in cardiovascular pathophysiology.

Dario Diviani,Erica Reggi,Miroslav Arambasic,Stefania Caso,Darko Maric

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research（2016）

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摘要

Heart and blood vessels ensure adequate perfusion of peripheral organs with blood and nutrients. Alteration of the homeostatic functions of the cardiovascular system can cause hypertension, atherosclerosis, and coronary artery disease leading to heart injury and failure.

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关键词

A kinase anchoring protein (AKAP),Protein kinase A (PKA),Signaling,Cardiac remodeling,Cardiomyocyte,Vascular smooth muscle cells

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