Investigation of one-lung ventilation postoperative cognitive dysfunction and regional cerebral oxygen saturation relations

Objective To explore the relationship of postoperative cognitive dysfunction (POCD) in one-lung ventilation (OLV) patients and regional cerebral oxygen saturation (rSO 2 ). Methods Twenty-nine male and twenty-one female cases of OLV received thoracic surgery, with American Standards Association (ASA) physical status being at Grades I–III. Neuropsychological tests were performed on the day before operation and 7 d after operation, and there was an intraoperative continuous monitoring of rSO 2 . The values of rSO 2 before anesthesia induction ( t 1 ), at the beginning of OLV ( t 2 ), and at the time of OLV 30 min ( t 3 ), OLV 60 min ( t 4 ), the end of OLV ( t 5 ), and the end of surgery ( t 6 ) were recorded. The intraoperative average of rSO 2 ( rSO_2 ), the intraoperative minimum value of rSO 2 (rSO 2, min ), and the reduced maximum percentage of rSO 2 (rSO 2,