Analysis of c-KIT exon 11 mutations in canine gastrointestinal stromal tumours.

•We assessed c-KIT exon 11 mutations in canine gastrointestinal stromal tumors.•RT-PCR had a higher detection rate (34/46; 73.9%) than conventional PCR (15/46; 32.6%).•Diffuse or partial KIT immunostaining was detected in the tumor.•Neither pattern was significantly associated with c-KIT exon 11 mutation status.•RT-PCR was more sensible for detecting c-KIT mutations than conventional PCR.