EZH2 phosphorylation regulates Tat-induced HIV-1 transactivation via ROS/Akt signaling pathway.

Hong-Sheng Zhang,Yang Liu,Tong-Chao Wu,Guang-Yuan Du,Feng-Juan Zhang

FEBS Letters（2015）

引用 12|浏览5

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摘要

•Tat induces HIV-1 transactivation through inhibiting EZH2.•Tat-induced EZH2 phosphorylation is ROS/Akt dependent.•EZH2 phosphorylation is correlated with Tat-induced transactivation.

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关键词

HIV-1,Enhancer of zeste homolog 2,Reactive oxygen species,AKT

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