Nitrogen mustard hydrochloride-induced acute respiratory failure and myelosuppression: A case report.
EXPERIMENTAL AND THERAPEUTIC MEDICINE(2015)
Abstract
Nitrogen mustards are chemical agents that are similar to sulfur mustards, with similar toxicities. The present study describes a case of nitrogen mustard-induced acute respiratory failure and myelosuppression in a 33-year-old man. The patient, who was accidentally exposed to nitrogen mustard hydrochloride in a pharmaceutical factory, exhibited severe inhalation injury and respiratory symptoms. Laboratory tests revealed reduced white blood cell counts and lowered platelet levels during the first 6 days after the skin exposure to nitrogen mustard. Following treatment with mechanical ventilation, immunity-enhancing agents and nutritional supplements for 1 month, the patient successfully recovered and was released from hospital.
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Key words
nitrogen mustard hydrochloride,respiratory failure,myelosuppression
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