Multi-laboratory validation of SkinEthic HCE test method for testing serious eye damage/eye irritation using liquid chemicals.

Nathalie Alepee,V Leblanc,Els Adriaens,M H Grandidier,Damien Lelievre,Marisa Meloni,L Nardelli,C S Roper, E Santirocco,F Toner,A Van Rompay,J Vinall,Jose Cotovio

Toxicology in Vitro（2016）

Cited 31|Views14

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Abstract

A prospective multicentric study of the reconstructed human corneal epithelial tissue-based in vitro test method (SkinEthic™ HCE) was conducted to evaluate its usefulness to identify chemicals as either not classified for serious eye damage/eye irritation (No Cat.) or as classified (Cat. 1/Cat. 2) within UN GHS.

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Key words

BCOP,BLR,C,CAS RN,Cat 1,Cat 2,CI,CM,CO,CRL,EIT,EITL,ESAC,EURL ECVAM,HCE,ICCVAM,ICE,LO,NgC,NC,NICEATM,No Cat,NSC,NSCliving,NSCkilled,NSMTT,MTT,OD,OECD,PC,PBS,RhCE,STE,S.O.P.,TG,UN GHS,VITO,VMG,VRM,WLR

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