Factors influencing naproxen metabolite interference in total bilirubin assays.
Clinical Biochemistry(2016)
摘要
•Naproxen metabolite ODMN interferes with some total bilirubin assays.•Acidic pH of Jendrassik-Grof direct bilirubin reagents prevents reaction with ODMN.•Positive ODMN interference depends on primary wavelength of endpoint measurement.•The AU total bilirubin assay is reliable in the setting of naproxen overdose.
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关键词
Naproxen,O-desmethylnaproxen,Bilirubin,Interference,Spectrophotometry,AU,DxC
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