Modulation of p53 during bacterial infections
NATURE REVIEWS MICROBIOLOGY（2015）
摘要
It has recently been suggested that p53, which regulates the survival and metabolism of host cells, is commonly manipulated by intracellular bacterial pathogens. In this Progress article, Siegl and Rudel discuss mechanisms of p53 manipulation and consider the consequences for pathogenesis.
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关键词
Bacterial pathogenesis, Bacterial host response, Bacterial immune evasion, DNA damage and repair, Stress signalling
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