Substrate-binding specificity of chitinase and chitosanase as revealed by active-site architecture analysis.
Carbohydrate Research(2015)
Abstract
•The sequence profiles of the chitosanase and chitinase active sites are constructed.•Substrate recognition is supported by hydrogen bonds with C2 functional groups.•CH–π interactions contribute to tighter binding and processivity.
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Key words
Chitinase,Chitosanase,Active-site architecture,Substrate-binding specificity
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