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Age-dependent alterations of voltage-gated Na(+) channel isoforms in rat sinoatrial node.

Xin Huang,Yuan Du,Pei Yang, Shienfong Lin,Yutao Xi,Zhao Yang,Aiqun Ma

Mechanisms of Ageing and Development（2015）

Cited 13|Views11
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Abstract
•We examine the expression of NaCh α subunit isoforms in rat SAN during aging.•We examine the expression of NaCh β subunit isoforms in rat SAN during aging.•We test the contribution of NaCh to the automaticity of rat SAN during aging.
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Key words
Aging,Automaticity,Optical mapping,Sodium channel,Sinoatrial node
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