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A new vertebrate SUMO enzyme family reveals insights into SUMO-chain assembly

Nathalie Eisenhardt,Viduth K Chaugule,Stefanie Koidl,Mathias Droescher,Esen Dogan, Jan Rettich,Päivi Sutinen,Susumu Y Imanishi,Kay Hofmann,Jorma J Palvimo,Andrea Pichler

NATURE STRUCTURAL & MOLECULAR BIOLOGY（2015）

Cited 81|Views16
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Abstract
The SUMO E3 ligase ZNF451 is a representative member of a new class of SUMO enzymes that execute catalysis via tandem SUMO-interaction motifs, thus allowing efficient SUMO-chain formation.
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Key words
Biochemistry,Enzyme mechanisms,Life Sciences,general,Protein Structure,Membrane Biology,Biological Microscopy
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