Assessing the Optimal Timing for Early Salvage Radiation Therapy in Patients with Prostate-specific Antigen Rise After Radical Prostatectomy.

Nicola Fossati,R Jeffrey Karnes,Cesare Cozzarini,Claudio Fiorino,Giorgio Gandaglia,Steven Joniau,Stephen A Boorjian,Gregor Goldner,Wolfgang Hinkelbein,Karin Haustermans,Bertrand Tombal,Shahrokh F Shariat,Pierre I Karakiewicz, Francesco Montorsi,Hein Van Poppel,Thomas Wiegel,Alberto Briganti

European Urology（2016）

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摘要

Cancer control after early salvage radiation therapy (eSRT) depends on pretreatment prostate-specific antigen (PSA) level and is highest in men with at least two of the following pathologic features: pT3b/pT4 disease, pathologic Gleason score ≥8, and negative surgical margins. Conversely, the benefit of eSRT is less evident in men with favourable disease at radical prostatectomy despite PSA rise.

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关键词

Prostatic neoplasms,Neoplasm recurrence,Biochemical tumour markers,Radiotherapy,Salvage therapy

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