Comparing four different ALK antibodies with manual immunohistochemistry (IHC) to screen for ALK-rearranged non-small cell lung cancer (NSCLC).

Qin Shen, Xuan Wang,Bo Yu,Shanshan Shi,Biao Liu,Yanfen Wang,Qiuyuan Xia,Qiu Rao,Xiaojun Zhou

Lung Cancer（2015）

引用 21|浏览25

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摘要

•Compared four different ALK antibodies for screening ALK-rearranged NSCLC via IHC.•The staining of manual IHC (clone 1A4) and Ventana IHC had high concordance.•Manual IHC (1A4) can be a preferred pre-screening for ALK-rearranged NSCLC patients.

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关键词

Non-small cell lung cancer (NSCLC),Anaplastic lymphoma kinase (ALK) gene rearrangement,Immunohistochemistry (IHC),Antibody 1A4/1H7

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