Long-Term Survival in Gliosarcoma with Radiation-Induced Meningeal Sarcomas: Case Report and Molecular Features
Journal of Cancer Research and Therapeutics/Journal of cancer research and therapeutics(2015)
Abstract
Gliosarcoma is a rare primary malignant tumor of the central nervous system with poor prognosis. The median survival time of this disease ranges from 6 months to 14.8 months. However, a computer literature search indicated few long-term survivors. We investigated a case of a survivor of gliosarcoma with radiation-induced meningeal sarcomas, who showed no indication of recurrence for more than 9 years. A battery of molecular studies was performed to develop a molecular profile of this unique patient. We also reviewed the distinct clinical and molecular features of the tumor.
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Key words
Gliosarcoma,long-term survival,meningeal sarcomas,molecular profile,radiation
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