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Loss-of-function variants in ATM confer risk of gastric cancer

Hannes Helgason,Thorunn Rafnar,Halla S Olafsdottir,Jon G Jonasson,Asgeir Sigurdsson,Simon N Stacey,Adalbjorg Jonasdottir,Laufey Tryggvadottir,Kristin Alexiusdottir,Asgeir Haraldsson,Louise le Roux,Julius Gudmundsson,Hrefna Johannsdottir,Asmundur Oddsson,Arnaldur Gylfason,Olafur T Magnusson,Gisli Masson,Thorvaldur Jonsson,Halla Skuladottir,Daniel F Gudbjartsson,Unnur Thorsteinsdottir,Patrick Sulem,Kari Stefansson

NATURE GENETICS（2015）

引用 131|浏览103
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摘要
Hannes Helgason, Kari Stefansson and colleagues report an association study of gastric cancer susceptibility based on whole-genome sequencing in the Icelandic population. They find that loss-of-function variants in ATM confer risk of gastric cancer.
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genome wide association studies
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