Different immune cells mediate mechanical pain hypersensitivity in male and female mice
Nature neuroscience(2015)
摘要
large literature has demonstrated the important role of spinal microglia in chronic pain processing. This paper demonstrates that microglia are required in male but not female mice. In female mice, a similar function appears to be subserved by adaptive immune cell, likely T lymphocytes.
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关键词
mechanical pain hypersensitivity,immune,mice
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