Interferon-γ regulates cellular metabolism and mRNA translation to potentiate macrophage activation

Xiaodi Su,Yingpu Yu,Yi Zhong,Eugenia G Giannopoulou,Xiaoyu Hu,Hui Liu,Justin R Cross,Gunnar Rätsch,Charles M Rice,Lionel B Ivashkiv

Nature immunology（2015）

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摘要

Interferon-γ (IFN-γ) primes macrophages to undergo proinflammatory activation. Ivashkiv and colleagues detail the translational and metabolic program triggered in human macrophages after IFN-γ treatment.

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nature immunology, science

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