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Structure of human ST8SiaIII sialyltransferase provides insight into cell-surface polysialylation

Gesa Volkers,Liam J Worrall,David H Kwan,Ching-Ching Yu,Lars Baumann,Emilie Lameignere,Gregory A Wasney,Nichollas E Scott,Warren Wakarchuk,Leonard J Foster,Stephen G Withers,Natalie C J Strynadka

Nature structural & molecular biology（2015）

Cited 65|Views27
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Abstract
Structural studies of human polysialyltransferase ST8SialII in apo form and in complex with donor sugar and sulfated glycan acceptor shed light on the substrate binding and specificity as well as the catalytic activity of this class of polysialyltransferases.
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nature structural and molecular biology, science
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