The chromatin remodeler Brg1 activates enhancer repertoires to establish B cell identity and modulate cell growth
NATURE IMMUNOLOGY(2015)
摘要
B lineage development requires the transcription factors E2A, EBF1, Foxo1 and Ikaros. Murre and colleagues show that these factors gain access to lineage-specific enhancer sites by the action of the chromatin remodeler Brg1.
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nature immunology, science
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