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The potential of sec-butylpropylacetamide (SPD) and valnoctamide and their individual stereoisomers in status epilepticus.

Tawfeeq Shekh-Ahmad,Hafiz Mawasi,John H McDonough,Boris Yagen,Meir Bialer

Epilepsy & Behavior（2015）

Cited 20|Views7
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Abstract
sec-Butylpropylacetamide (SPD) is a one-carbon homologue of valnoctamide (VCD), a chiral constitutional isomer of valproic acid's (VPA) corresponding amide — valpromide.
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Key words
New antiepileptic drugs,Benzodiazepine-resistant status epilepticus,Stereoselective pharmacokinetic and pharmacodynamic analysis,Chiral switch
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