Deletion of aquaporin-4 is neuroprotective during the acute stage of micro traumatic brain injury in mice.

Fengyin Liang,Chuanming Luo,Guangqing Xu,Fengjuan Su,Xiaofei He,Simei Long,Huixia Ren,Yaning Liu,Yanqing Feng,Zhong Pei

Neuroscience Letters（2015）

引用 34|浏览21

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摘要

•Two-photon microscopy was use to examine the role of AQP4 in micro TBI.•AQP4 deletion reduced cells death, astrocytes swelling and lesion volume.•Treatment inhibiting AQP4 can be used to protect micro brain injury.

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关键词

Aquaporin-4 (AQP4),Micro traumatic brain injury,Acute stage,Cerebral edema

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