Bioluminescent whole-cell reporter gene assays as screening tools in the identification of antimicrobial natural product extracts
Journal of Microbiological Methods(2015)
摘要
We describe novel tools, bioluminescent whole-cell reporter gene assays, for facilitating the use of natural products in antimicrobial drug discovery. As proof-of-concept, a plant extract library was screened and follow-up experiments were carried out. Primary results can be obtained in 2–4h with high sensitivity, leading to significant improvements of the process.
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B,RLU,Neg
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