Chrome Extension
WeChat Mini Program
Use on ChatGLM
VIPCreated with Sketch.

P53 suppresses cell proliferation, metastasis, and angiogenesis of osteosarcoma through inhibition of the PI3K/AKT/mTOR pathway.

Song Ruipeng,Tian Ke,Wang Weidong,Wang Limin

International Journal of Surgery（2015）

Cited 49|Views10
No score
Abstract
•P53 potently inhibited cell proliferation in osteosarcoma cell line (MG63) and in human normal osteoblasts (hFOB1.19) in vitro.•An inhibitory effect of P53 on metastasis was observed in osteosarcoma cell line MG63.•P53 suppresses cell proliferation and angiogenesis of osteosarcoma through inhibition of the PI3K/AKT/mTOR pathway.
More
Translated text
Key words
Osteosarcoma,MG63,P53,Mammalian target of rapamycin (mTOR),PI3K/AKT/mTOR pathway,Invasion,Migration,Target therapy
AI Read Science
Must-Reading Tree
Example
Generate MRT to find the research sequence of this paper
Chat Paper
Summary is being generated by the instructions you defined