Identification of Distinct Conformations of the Angiotensin-II Type 1 Receptor Associated with the Gq/11 Protein Pathway and the Β-Arrestin Pathway Using Molecular Dynamics Simulations*
Journal of Biological Chemistry（2015）
Key words
angiotensin II,G protein-coupled receptor (GPCR),molecular dynamics,protein conformation,receptor structure-function,AT1 receptor,AT1R,activation mechanism,biased signaling,functional selectivity
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