Comparative analysis of two types of CXCL8 from Japanese flounder (Paralichthys olivaceus).

Developmental & Comparative Immunology(2015)

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摘要
•Identity of 41.2% was showed between CXCL8_L1a and CXCL8_L1b.•Both CXCL8_L1a and CXCL8_L1b belonged to CXCL8_L1 group.•CXCL8_L1a was involved in anti-E. tarda immune response, and CXCL8_L1b was involved in anti-VHSV immune response.•Both CXCL8_L1a and CXCL8_L1b caused local recruitment of inflammatory cells.•CXCL8_L1b significantly induced the transcription level of IgM.
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关键词
CXCL8_L1a,CXCL8_L1b,Japanese flounder,Immune response,Chemotaxis
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