Evolution of the complement system C3 gene in Antarctic teleosts.

Molecular Immunology(2015)

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摘要
•Antarctic teleost C3 genes underwent Darwinian selection.•Positive selection modified sites crucial for the flexibility of the C3 molecule.•Domain movements were found more pronounced in Antarctic molecules.
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关键词
α′NT,ANATO,C3,C345C,CS,CUB,LINCS,LNK,MD,MG,RACE,RMSD,RMSF,SAR,TED
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