Exploring the benefits of antibody immune response in HIV-1 infection using a discrete model
Mathematical Medicine and Biology: A Journal of the IMA（2016）
摘要
The role of antibodies in HIV-1 infection is investigated using a discrete-time mathematical model that considers cell-free and cell-associated transmission of the virus. Model analysis shows that the effect of each type of antibody is dependent on the stage of the infection. Neutralizing antibodies are efficient in controlling the viral levels in the early days after seroconversion and antibodies...
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关键词
antibodies,HIV infection,antibody-dependent cell-mediated virus inhibition,antibody-dependent cellular cytotoxicity
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