Augmented Rac1 Expression and Activity are Associated with Oxidative Stress and Decline of β Cell Function in Obesity.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology（2015）
摘要
Rac1 might contribute to oxidative stress systemically and locally in the pancreas in obesity. The excessive activation and expression of Rac1 in obesity were associated with β cell dysfunction through ROS production.
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