Production and characterization of monospecific and bispecific antibodies against dengue virus NS1 protein.

•Quadromas and hybridomas against dengue NS1 protein for immunodiagnostic assay.•Distinct advantages over other conventional probes used in diagnostic assays.•BsMAbs have intrinsic binding sites to any two molecules in a pre-determined order.•Bispecific antibodies function as excellent immunoprobes.