Shiga toxin-1 Decreases Endothelial Cell Tissue Factor Pathway Inhibitor Not Co-localized with Tissue Factor on the Cell Membrane.
Thrombosis Research(2015)
摘要
•Shiga toxin-1 + TNFα enhances procoagulant tissue factor (TF) on endothelial cells.•This results from a decrease in “free” cell surface TF pathway inhibitor (TFPI).•The enhanced procoagulant TF is not due to an increase in “free” TF.
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