Effects of insulin-like growth factor-1 on the assembly and secretion of very low-density lipoproteins in cow hepatocytes in vitro.

General and Comparative Endocrinology(2016)

Cited 4|Views26
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Abstract
•IGF-1 increased the ApoB100, ApoE, MTTP and LDLR expression in cow hepatocytes.•IGF-1 increased the VLDL assembly and secretion in cow hepatocytes.•Impairment of IGF-1 expression decreased the VLDL assembly in cow hepatocytes.
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Key words
VLDL,NEFA,IGF-1,ApoB100,ApoE,MTTP,LDLR,NEB,TG,GH,JAK2-STAT5,PBS,NAFLD,MAPK/JNK,MAPK/ERK,PI3-K
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