Four-Year Evolution Of Insulin Regimens, Glycaemic Control, Hypoglycaemia And Body Weight After Starting Insulin Therapy In Type 2 Diabetes Across Three Continents

•We describe how insulin therapy evolves in clinical practice over 4 years in >2000 people with T2DM.•Initial insulin was basal 52%, premix 23%, mealtime+basal 14%, mealtime 8%, other 3%.•At 4 years this was 30%, 25%, 33%, 2% and 5%, with 5% not on insulin.•HbA1c change was −2.0 (SD 2.2)%, similar by final insulin regimen, and stable over 4 years.•Hypoglycaemia prevalence was <20% of people in all years (1–4 separately).