The serotonin 5-HT₁A receptor agonist tandospirone improves executive function in common marmosets.

Behavioural Brain Research(2015)

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摘要
•The 5-HT1A receptor agonist tandospirone improved marmosets executive function.•Blonanserin had no detrimental effect on marmoset executive function.•Co-treatment with tandospirone and blonanserin improved marmosets executive function.•Tandospirone given with other antipsychotics did not affect animals’ executive function.•Tandospirone is a promising candidate for the treatment of cognitive impairment.
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关键词
Antipsychotic,Common marmoset,Executive function,Object retrieval with detour,Schizophrenia,Serotonin 5-HT1A receptor
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