Clinical usefulness of low tube current scanning with full reconstruction and automatic patient motion correction (APMC) reconstruction in a prospective ECG-gated coronary CT angiography using 320-row area detector CT]

The purpose of this study is to validate the clinical usefulness of Advanced Patient Motion Correction (APMC) reconstruction when motion artifacts were observed in a prospective ECG-gated coronary CT angiography (CCTA), which was acquired by low tube current scanning with full reconstruction using 320-row area detector CT (0.275 s/rot.).Of 530 consecutive CCTA, we selected 119 patients (M/F: 71/48, Age: 69 ± 11 y, BMI: 23.5 ± 2.5) with (RR-PQ) ≥ 968 ms before scanning, and performed a CCTA with low tube current scanning [30% of usual tube current (30%mA)], adaptive iterative dose reduction 3D, and full reconstruction. Image quality for motion artifacts was subjectively evaluated using a 3-point scale (excellent, acceptable, and unacceptable).Of 119, 102 CCTA had "excellent" images (group A) and 17 had "acceptable" images (group B). The APMC and half reconstruction were retried in the 17 CCTA with "acceptable" images. Finally, all CCTA became "excellent" images. The RR-PQ of group B during scanning (966 ± 80 ms) was significantly (P = 0.0001) shorter than group A (1,088 ± 123 ms). Each image noise (standard deviation of CT value) of aorta, left atrium, and left ventricle was 21.7 ± 2.3, 24.7 ± 2.3, 24.5 ± 2.4 in full, 25.7 ± 2.2, 29.0 ± 3.4, 28.2 ± 2.7 in APMC, and 30.4 ± 2.8, 34.3 ± 4.2, 33.3 ± 2.9 HU in half reconstruction. Mean dose-length product of all patients was 66.2 ± 34.4 mGy · cm."Excellent" CCTA images can be obtained in 85.7% of patients with (RR-PQ)≥ 968 ms by full reconstruction. APMC is useful for motion artifacts and image noise reduction when patient' s HR increases during scanning rather than half reconstruction.